Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Our findings support the beneficial effect of magnesium on reducing BP among populations with hypertension and hypomagnesemia, although effects should be interpreted with caution due to high heterogeneity of studies. Larger, well-designed studies assessing higher magnesium doses are needed to refine the dose-response relationship between magnesium intake and BP and identify potential optimal supplementation strategies for subpopulations.
Authors
- Buna Bhandari (ORCID: https://orcid.org/0000-0002-0102-8844)
- Xiaoyue Xu (ORCID: https://orcid.org/0000-0003-4787-6547)
- Rhian M. Touyz (ORCID: https://orcid.org/0000-0003-0670-0887)
- Katie Harris (ORCID: https://orcid.org/0000-0003-2444-2869)
- Aletta Elisabeth Schutte (ORCID: https://orcid.org/0000-0001-9217-4937)
- Zoe Argeros
Institutions
- Florida State University (US)
- The University of Sydney (AU)
- Florida A&M University - Florida State University College of Engineering (US)
- McGill University Health Centre (CA)
- The George Institute for Global Health (AU)
- Harvard Global Health Institute (US)
Publication Details
- Journal
- Hypertension
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25129
- Citations
- 4
- Primary Topic
- Magnesium in Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 4.48