Mind the gap – Interthalamic adhesions in prodromal and clinical Alzheimer’s disease
The study found no overall differences in IA prevalence or its variants related to prodromal or clinical AD. Still, elevated Aβ42, p-Tau levels, and larger thalamic volume were linked to a higher likelihood of a broad IA. These findings suggest that the IA may be involved in prodromal AD pathophysiological processes.
Authors
- Emmanuel J. Barbeau (ORCID: https://orcid.org/0000-0003-0836-3538)
- Gonzalo Forno (ORCID: https://orcid.org/0000-0003-2739-6028)
- Rachel H. Tan (ORCID: https://orcid.org/0000-0002-0385-4090)
- Julie Vidal (ORCID: https://orcid.org/0009-0006-7711-3080)
- John P. Aggleton (ORCID: https://orcid.org/0000-0002-5573-1308)
- Michael Hornberger (ORCID: https://orcid.org/0000-0002-2214-3788)
- Perry J. Rush
Institutions
- University of East Anglia (GB)
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- UNSW Sydney (AU)
- Instituto de Neurociencia Biomédica (CL)
- Centre de recherche cerveau et cognition (FR)
- University of Southampton (GB)
- Cardiff University (GB)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111559
- Citations
- 1
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39