Intravenous recombinant human prourokinase for acute ischemic stroke: a network meta-analysis

Both 35 mg and 50 mg rhPro-UK improve early neurological outcomes. However, 40 mg rhPro-UK + ALT may offer the most favorable efficacy-safety profile. Further trials are warranted to optimize dosing strategies.

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Publication Details

Journal
Minerva Medica
Published
2025-09-26
DOI
https://doi.org/10.23736/s0026-4806.25.09737-x
Primary Topic
Bee Products Chemical Analysis
Type
article
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article

Intravenous recombinant human prourokinase for acute ischemic stroke: a network meta-analysis

Maurus Marques de Almeida Holanda, J. Mancha Ramos, João V Fernandes
Minerva Medica
Bee Products Chemical Analysis
article

Intravenous recombinant human prourokinase for acute ischemic stroke: a network meta-analysis

Maurus Marques de Almeida Holanda, J. Mancha Ramos, João V Fernandes
article en

Abstract

Both 35 mg and 50 mg rhPro-UK improve early neurological outcomes. However, 40 mg rhPro-UK + ALT may offer the most favorable efficacy-safety profile. Further trials are warranted to optimize dosing strategies.

Minerva MedicaVol. 116(6)
Universidade Federal da Paraíba (BR)
Openalex Percentile: Top 76%
Bee Products Chemical Analysis
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Intravenous recombinant human prourokinase for acute ischemic stroke: a network meta-analysis — Maurus Marques de Almeida Holanda, J. Mancha Ramos, et al. · Minerva Medica (2025) | TGRS Research Map | TGRS