Genomic and clinical features in young women with estrogen receptor-positive, HER2-negative breast cancer

Young women with ER-positive, HER2-negative EBC have poorer outcomes. Ki67, in particular, is a poor prognostic marker in this group. Genomic profiling improves risk stratification and highlights unique tumor biology, supporting personalized treatment strategies.

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Publication Details

Journal
ESMO Open
Published
2025-09-24
DOI
https://doi.org/10.1016/j.esmoop.2025.105764
Citations
2
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
3.04
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article

Genomic and clinical features in young women with estrogen receptor-positive, HER2-negative breast cancer

María Vidal, Pedro Jares, Bárbara Adamo, Francesco Schettini et al.
2 citations
ESMO Open
Advanced Breast Cancer Therapies
3.04
article

Genomic and clinical features in young women with estrogen receptor-positive, HER2-negative breast cancer

María Vidal, Pedro Jares, Bárbara Adamo, Francesco Schettini, Fara Brasó‐Maristany, C. Bugés Sánchez, R Gómez-Bravo, Isaac Cebrecos, Pol Giménez‐Xavier, Javier Carrillo, Tomás Pascual, Benjamín Walbaum, Patricia Galván, Olga Martínez‐Sáez, Antonio Martı́nez, Isabel García-Fructuoso, Esther Sanfeliu, Milana Bergamino, Laura Angelats, Núria Chic, M. Muñoz, Melinda González Concepción, Aleix Prat, Elia Seguí, Joan Anton Puig‐Butillé, José Antonio Arz Sola, M. Rey, A. Rodriguez-Hernandez
article en
2 citations

Abstract

Young women with ER-positive, HER2-negative EBC have poorer outcomes. Ki67, in particular, is a poor prognostic marker in this group. Genomic profiling improves risk stratification and highlights unique tumor biology, supporting personalized treatment strategies.

ESMO OpenVol. 10(10)
Clínica Alemana (CL), Hospital Clínic de Barcelona (ES)
Openalex Percentile: Top 8%
Advanced Breast Cancer Therapies
3.04
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