Diagnostic accuracy of the <scp>WHO</scp> clinical staging system for detection of immunologically defined advanced <scp>HIV</scp> disease: A systematic review and meta‐analysis
WHO clinical staging alone shows low accuracy for detecting advanced HIV disease, risking both missed diagnoses and overtreatment. CD4 testing remains essential for accurately identifying and managing advanced HIV disease.
Authors
- Nathan Ford (ORCID: https://orcid.org/0000-0001-8238-4228)
- Akitoshi Ueno
- Ajay Rangaraj
- Augustine Talumba Choko (ORCID: https://orcid.org/0000-0001-6095-9430)
- David Stephen Lawrence (ORCID: https://orcid.org/0000-0002-5439-4039)
- Peter MacPherson (ORCID: https://orcid.org/0000-0002-0329-9613)
- Robina Semphere (ORCID: https://orcid.org/0000-0001-9774-6236)
- Kelvin T. Balakasi (ORCID: https://orcid.org/0000-0003-1150-1217)
- Ross Murtagh (ORCID: https://orcid.org/0000-0002-4409-0330)
- Madalo Mukoka (ORCID: https://orcid.org/0000-0001-9656-8255)
- Seyed Alireza Mortazavi (ORCID: https://orcid.org/0000-0002-4027-620X)
- Hussein H. Twabi (ORCID: https://orcid.org/0000-0003-4473-296X)
- Joseph N Jarvis (ORCID: https://orcid.org/0000-0003-1459-5554)
- Josephine Ives
Institutions
- University of Liverpool (GB)
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- Liverpool School of Tropical Medicine (GB)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Kamuzu Central Hospital (MW)
- London School of Hygiene & Tropical Medicine (GB)
- World Health Organization (CH)
- Public Health Scotland (GB)
- Botswana Harvard AIDS Institute Partnership (BW)
- Kamuzu University of Health Sciences (MW)
- University of Glasgow (GB)
Publication Details
- Journal
- HIV Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1111/hiv.70122
- Citations
- 1
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 1.40