Comparative Single-Cell Transcriptome Analysis of c-Met Receptor Expressing and Non-Expressing Projection Neurons in the Developing Frontal and Visual Cortices
The current findings provide support for the hypothesis that Met+ projection neurons are in a less mature state than Met- projection neurons within the same subclass. Further, the data are consistent with converging lines of biochemical and electrophysiological evidence that MET contributes to asynchronous maturation of developing cortical circuits.
Authors
- Pat Levitt (ORCID: https://orcid.org/0000-0002-9717-1695)
- Kathie L. Eagleson (ORCID: https://orcid.org/0000-0003-2819-1817)
- Ramin Ali Marandi Ghoddousi (ORCID: https://orcid.org/0000-0001-9867-1731)
- Zia Rady
Institutions
- University of Southern California (US)
- Children's Hospital of Los Angeles (US)
Publication Details
- Journal
- Developmental Neuroscience
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1159/000548617
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Children's Hospital Los Angeles
- Saban Research Institute
- National Institute of Mental Health