Unveiling the Causal Roles of the Oral Microbiome-Host Metabolism-Inflammation Axis in Periodontitis: A Mendelian Randomisation Study.
This study provides the first systematic genetic evidence for the causal roles and potential mediation mechanisms of oral microbiota, blood metabolites, and inflammatory proteins in the development of periodontitis. The findings offer new insights into the role of the oral microbiome-host metabolism-inflammation axis in periodontitis aetiology.
Authors
- Yingying Hu (ORCID: https://orcid.org/0000-0002-5653-8892)
- Ziyu Zhao
- Weihong Yang
Publication Details
- Journal
- PubMed
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3290/j.ohpd.c_2284
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00