Educational attainment and mental health outcomes: A within-sibship Mendelian randomization study

Higher EA or genetic liability to education reduces symptoms of anxiety, neuroticism, and psychotropic medication use. These mental health benefits do not seem to be explained by EA-linked genetic nurture or demographic factors. Regarding depression, results were less conclusive due to imprecise estimates, though beneficial effects of genetic liability to higher EA are possible and warrant further investigation.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725101736
Primary Topic
Cognitive Abilities and Testing
Type
article
Field-Weighted Citation Impact
0.00

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article

Educational attainment and mental health outcomes: A within-sibship Mendelian randomization study

Laxmi Bhatta, George Davey Smith, María Fernanda Vinueza‐Veloz, Paul Remy Jones et al.
Psychological Medicine
Cognitive Abilities and Testing
article

Educational attainment and mental health outcomes: A within-sibship Mendelian randomization study

Laxmi Bhatta, George Davey Smith, María Fernanda Vinueza‐Veloz, Paul Remy Jones, Martin Tesli, Neil M Davies, Øyvind Næss, Ben Michael Brumpton
article en

Abstract

Higher EA or genetic liability to education reduces symptoms of anxiety, neuroticism, and psychotropic medication use. These mental health benefits do not seem to be explained by EA-linked genetic nurture or demographic factors. Regarding depression, results were less conclusive due to imprecise estimates, though beneficial effects of genetic liability to higher EA are possible and warrant further investigation.

Psychological MedicineVol. 55
Oslo University Hospital (NO), Norwegian Institute of Public Health (NO), University of Oslo (NO), Norwegian University of Science and Technology (NO), University of Bristol (GB), St Olav's University Hospital (NO), Diakonhjemmet Hospital (NO), Østfold Hospital Trust (NO), University College London (GB)
Norges Teknisk-Naturvitenskapelige Universitet, University of Bristol, Helse Midt-Norge, Norges Forskningsråd, National Institutes of Health, Fakultet for medisin og helsevitenskap, Norges Teknisk-Naturvitenskapelige Universitet, Medical Research Council, Faculty of Medicine and Health, University of Sydney, Norwegian Institute of Public Health, National Institute of Mental Health
Openalex Percentile: Top 73%
Cognitive Abilities and Testing
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Educational attainment and mental health outcomes: A within-sibship Mendelian randomization study — Laxmi Bhatta, George Davey Smith, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS