Herring oil rich in long-chain monounsaturated fatty acid (C22: 1n-11) lowers plasma lipids and modulates fatty acid composition, oxidation, and inflammation in rats
These findings suggest that intake of CETO3<sup>®</sup> oil lowers plasma lipids, potentially through enhanced peroxisomal and mitochondrial FA oxidation. The shift in FA composition, with reduced n-6 FAs and increased n-3 and n-11 MUFAs, indicates an anti-inflammatory effect. CETO3<sup>®</sup> oil also appears safe, as hematological parameters, glucose tolerance, and organ weights remained unaffected.
Authors
- Jannike Øyen (ORCID: https://orcid.org/0000-0002-5590-5136)
- Bodil Bjørndal (ORCID: https://orcid.org/0000-0001-9718-5117)
- Lise Madsen (ORCID: https://orcid.org/0000-0003-4468-1947)
- Simon N. Dankel (ORCID: https://orcid.org/0000-0001-6972-1824)
- Pavol Bohov (ORCID: https://orcid.org/0000-0002-0022-9273)
- Magne O. Sydnes (ORCID: https://orcid.org/0000-0001-9413-6969)
- Aurora Brønstad (ORCID: https://orcid.org/0000-0002-5511-5425)
- Arild Christian Rustan (ORCID: https://orcid.org/0000-0003-0963-5363)
- Ottar Kjell Nygard (ORCID: https://orcid.org/0000-0002-4885-1010)
- Siri Lunde Tungland (ORCID: https://orcid.org/0000-0002-8829-3412)
- Suzanne Brandt
- Hege G. Bakke
- Rolf K. Berge
- Thomas A. Aloysius
- Camilla H. Nundal
Institutions
- Western Norway University of Applied Sciences (NO)
- University of Oslo (NO)
- Haukeland University Hospital (NO)
- Norwegian Institute of Marine Research (NO)
- PCI Biotech (Norway) (NO)
- University of Bergen (NO)
- University of Stavanger (NO)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fnut.2025.1611166
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitetet i Bergen
- Haukeland Universitetssjukehus