Gender differences in symptom profiles of individuals being treated for mood disorders
Results suggest gender-specific phenotypes that differentially characterize mood disturbances, although effect sizes were small. Further research is needed to confirm these phenotypes and identify sexually dimorphic biomarkers or psychosocial exposures that may underlie gender differences. Understanding the heterogeneity of phenotypes can inform precision-based assessment and treatment of mood disorders, improving affective well-being of women and men in the long term.
Authors
- Sandra J. Weiss (ORCID: https://orcid.org/0000-0001-6700-8734)
- Sarah Nagle-Yang (ORCID: https://orcid.org/0000-0001-5024-9670)
- Bruce A. Cooper (ORCID: https://orcid.org/0000-0001-8932-4113)
- Ayşegül Özerdem (ORCID: https://orcid.org/0000-0002-9455-5896)
- Maria Muzik (ORCID: https://orcid.org/0000-0001-9888-8519)
- Diana I. Simeonova
- Heather A. Flynn
Institutions
- Florida State University (US)
- Mayo Clinic (US)
- Emory University (US)
- University of Michigan (US)
- WinnMed (US)
- Unity Health System (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Journal of Mood and Anxiety Disorders
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1016/j.xjmad.2025.100152
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00