Analysis of clinical characteristics of multifocal electroretinogram and microperimetry in patients with high myopia

To investigate the role of microperimetry (MP) and multifocal electroretinogram (mfERG) in evaluating macular function in high myopia METHODS: From January to June 2025, data from 42 patients (76 eyes) undergoing both MP and mfERG at Jinan Mingshui Eye Hospital were retrospectively analyzed. The impact of axial length, atrophic macular degeneration (Atrophic, Tractional, Neovascular, ATN) grade, and age on the results was compared RESULTS: MP and mfERG results in pathological myopia were significantly lower than the normal range. Significant differences in light sensitivity and best-corrected visual acuity (BCVA) were found across different axial lengths, ATN grades, and age groups (P < 0.05). For amplitude density, Ring3 and Ring4 showed significant differences among axial lengths (P < 0.05), while Rings 1-5 exhibited significant differences among ATN grades and age groups (P < 0.05). Further clarification is needed for latency differences among these variables CONCLUSION: MP and mfERG are valuable tools for assessing macular function changes in high myopia.