Efficacy of Oxycodone Combined With Thoracic Paravertebral Nerve Block for Postoperative Analgesia in Esophageal Cancer Surgery: A Retrospective Study

This study demonstrates that combining TPVB with oxycodone IV PCA provides superior analgesia, faster recovery, and better anti-inflammatory effects than sufentanil-based or single-modality regimens, with a low incidence of adverse events.These findings highlight a clinically effective multimodal strategy for postoperative pain control in esophageal cancer surgery. Based on the data, this approach may reduce chronic pain and improve recovery quality, supporting its broader clinical application.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2025-09-26
DOI
https://doi.org/10.1177/10600280251349200
Citations
1
Primary Topic
Cancer, Stress, Anesthesia, and Immune Response
Type
article
Field-Weighted Citation Impact
1.47
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article

Efficacy of Oxycodone Combined With Thoracic Paravertebral Nerve Block for Postoperative Analgesia in Esophageal Cancer Surgery: A Retrospective Study

Hang Zhou, Wensheng Zhang, Dongshui Liu, Weiwei Li et al.
1 citations
Annals of Pharmacotherapy
Cancer, Stress, Anesthesia, and Immune Response
1.47
article

Efficacy of Oxycodone Combined With Thoracic Paravertebral Nerve Block for Postoperative Analgesia in Esophageal Cancer Surgery: A Retrospective Study

Hang Zhou, Wensheng Zhang, Dongshui Liu, Weiwei Li, Fujun Wang, Huijian Shi, Yue Fang, Zhiyuan Huai
article en
1 citations

Abstract

This study demonstrates that combining TPVB with oxycodone IV PCA provides superior analgesia, faster recovery, and better anti-inflammatory effects than sufentanil-based or single-modality regimens, with a low incidence of adverse events.These findings highlight a clinically effective multimodal strategy for postoperative pain control in esophageal cancer surgery. Based on the data, this approach may reduce chronic pain and improve recovery quality, supporting its broader clinical application.

Annals of Pharmacotherapy
Affiliated Hospital of Taishan Medical University (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 15%
Cancer, Stress, Anesthesia, and Immune Response
1.47
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