A – 104 Early detection of cognitive disorders and dementia in hypertensive patients

Abstract Objective Hypertension is a significant risk factor for dementia, with hypertensive individuals experiencing a 4.8-fold increased risk. Current dementia diagnosis is time-consuming, and early detection tools are limited. Method Our two pilot studies analyzed 42,711 data points, including cognitive tests (SDMT, Stroop, memory games) and blood pressure monitoring. 261 participants completed cognitive tests, and 20 hypertensive individuals received MIND diet counseling and monitored blood pressure for three months, providing 1039 measurements. Results A normalized scoring system enabled cognitive test result comparisons, revealing significant differences between potentially affected and healthy groups. Subgroup analyses identified hypertension, endocrinological disorders, and incipient dementia in lower-performing individuals, while depression, post-COVID syndrome, and sleep apnea were noted in higher-performing individuals. Cognitive games improved memory and mood. Dietary advice enhanced energy and nutrient intake. Blood pressure improved in the intervention group, decreasing from 144/96 mmHg to 133/87 mmHg (systolic: -11.35 mmHg, diastolic: -9.7 mmHg). Conclusion These findings suggest that combining cognitive assessments with AI and dietary interventions can aid in early cognitive decline detection in hypertensive patients. Routine cognitive monitoring is recommended for hypertensive care.