Preoperative Immunonutritional Scores as Predictors of Mortality and Recurrence in Patients with Peritoneal Carcinomatosis Secondary to Serous Ovarian Cancer Undergoing Cytoreductive Surgery and HIPEC

Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) has become an increasingly preferred treatment for women with ovarian cancer presenting with peritoneal involvement. However, due to the high morbidity of HIPEC, accurate preoperative patient selection is essential. This study aimed to evaluate the prognostic value of immunonutritional indices—CALLY (C-reactive protein, albumin, lymphocyte) and Prognostic Nutritional Index (PNI)—in predicting early mortality and recurrence in patients undergoing CRS and HIPEC. A retrospective analysis was conducted on 49 female patients. Low CALLY (

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Journal
OSMANGAZİ JOURNAL OF MEDICINE
Published
2025-09-26
DOI
https://doi.org/10.20515/otd.1744552
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Preoperative Immunonutritional Scores as Predictors of Mortality and Recurrence in Patients with Peritoneal Carcinomatosis Secondary to Serous Ovarian Cancer Undergoing Cytoreductive Surgery and HIPEC

Yavuz Selim Angın, Akile Zengin, Elif Gündoğdu, Murat Ulaş et al.
OSMANGAZİ JOURNAL OF MEDICINE
Intraperitoneal and Appendiceal Malignancies
article

Preoperative Immunonutritional Scores as Predictors of Mortality and Recurrence in Patients with Peritoneal Carcinomatosis Secondary to Serous Ovarian Cancer Undergoing Cytoreductive Surgery and HIPEC

Yavuz Selim Angın, Akile Zengin, Elif Gündoğdu, Murat Ulaş, Orkhan Ulfanov, Mehmet Kılıç, Cengiz Ceylan, Elçin Telli
article en

Abstract

Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) has become an increasingly preferred treatment for women with ovarian cancer presenting with peritoneal involvement. However, due to the high morbidity of HIPEC, accurate preoperative patient selection is essential. This study aimed to evaluate the prognostic value of immunonutritional indices—CALLY (C-reactive protein, albumin, lymphocyte) and Prognostic Nutritional Index (PNI)—in predicting early mortality and recurrence in patients undergoing CRS and HIPEC. A retrospective analysis was conducted on 49 female patients. Low CALLY (

OSMANGAZİ JOURNAL OF MEDICINEVol. 47(6)
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi (TR), Ergani Devlet Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR)
Eskişehir Osmangazi Üniversitesi
Openalex Percentile: Top 58%
Intraperitoneal and Appendiceal Malignancies
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