Derivation of ultrasound and electrocardiogram cardiac reference ranges for Mus musculus using the collaborative cross and identification of new cardiac models
These new models allow a more natural, and therefore more translatable progression to a cardiac disease state, supporting development of strain-specific models for cardiac pathologies, ultimately allowing more accurate diagnoses and informative human relevant assessments.
Authors
- Krishna Patel (ORCID: https://orcid.org/0000-0002-4986-0955)
- Ivan Rusyn (ORCID: https://orcid.org/0000-0001-9340-7384)
- David W. Threadgill (ORCID: https://orcid.org/0000-0003-3538-1635)
- Brian R. Berridge (ORCID: https://orcid.org/0000-0003-1988-2819)
- Steve Leung (ORCID: https://orcid.org/0000-0003-2832-2258)
- Julia Popp (ORCID: https://orcid.org/0000-0003-4704-5954)
- Danila Cuomo (ORCID: https://orcid.org/0000-0003-4752-5819)
- Weihsueh A. Chiu (ORCID: https://orcid.org/0000-0002-7575-2368)
- Rachel Lynch (ORCID: https://orcid.org/0000-0001-8164-0744)
Institutions
- University of Kentucky (US)
- National Institute of Environmental Health Sciences (US)
- Texas A&M University (US)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12872-025-05156-y
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- U.S. Environmental Protection Agency