The Impact of Intraoperative Radiotherapy on Margin Positive Locally Advanced Rectal Cancer: A Propensity‐Matched Analysis of The National Cancer Database
This nationwide analysis suggests that adding IORT to treatment does not significantly improve overall survival in margin-positive rectal cancer patients. However, due to heterogeneity in patient selection and dosing, further prospective trials are warranted to clarify its clinical role.
Authors
- Brogan Catalano
- Salih Nafiz Karahan (ORCID: https://orcid.org/0000-0002-3610-7390)
- Mustafa Oruç (ORCID: https://orcid.org/0000-0002-7918-1689)
- Scott R. Steele (ORCID: https://orcid.org/0000-0003-1951-1516)
- Emre Görgün (ORCID: https://orcid.org/0000-0001-7725-3522)
- Metincan Erkaya (ORCID: https://orcid.org/0000-0002-4707-6059)
- Ali Alipouriani (ORCID: https://orcid.org/0000-0002-0438-3251)
- Jacob A. Miller (ORCID: https://orcid.org/0000-0001-6640-169X)
- Sudha R. Amarnath (ORCID: https://orcid.org/0000-0002-0852-3135)
Institutions
- Cleveland Clinic (US)
Publication Details
- Journal
- Journal of Surgical Oncology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1002/jso.70102
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00