Understanding time–activity curve and time‐integrated activity variations in radiopharmaceutical therapy challenge: Experience and results
The results of the TACTIC challenge demonstrate the large variability in TAC fitting despite the participants receiving identical input data. This highlights the fundamental role of TAC fitting methodology selection in the calculation of absorbed doses in RPT and successfully raises awareness of the need for greater harmonization in dosimetric approaches.
Authors
- Elisa Grassi (ORCID: https://orcid.org/0000-0003-3302-4351)
- Johannes Tran‐Gia (ORCID: https://orcid.org/0000-0001-9552-7750)
- Marta Cremonesi (ORCID: https://orcid.org/0000-0002-0230-9656)
- Johannes Heemskerk
- Oleksandra Ivashchenko (ORCID: https://orcid.org/0000-0001-8675-8987)
- Mattias Sandström (ORCID: https://orcid.org/0000-0002-5443-3122)
- Eero Hippeläinen
- Gerhard Glatting (ORCID: https://orcid.org/0000-0001-7916-1576)
- Deni Hardiansyah (ORCID: https://orcid.org/0000-0003-0984-8967)
- Jim O’Doherty (ORCID: https://orcid.org/0000-0003-2989-4485)
Institutions
- University College Dublin (IE)
- Uppsala University (SE)
- University Medical Center Groningen (NL)
- University of Helsinki (FI)
- Medical University of South Carolina (US)
- Universität Ulm (DE)
- Leiden University Medical Center (NL)
- Helsinki University Hospital (FI)
- University of Indonesia (ID)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- Medical Solutions (GB)
- Universitätsklinikum Würzburg (DE)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Technische Hochschule Ulm (DE)
- European Institute of Oncology (IT)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1002/mp.70043
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutscher Akademischer Austauschdienst
- Universitas Indonesia