Effects of olfactory enrichment on perioperative neurocognitive disorders in elderly patients undergoing orthopedic surgery: a study protocol of a multi-center randomized controlled trial
The trail has been registered in ClinicalTrial.gov with the Trial Registration Number of NCT06488807. Date of registration in the primary registry: June 15, 2024. The study is anticipated to start in March 2025. The anticipated primary completion date is December 31, 2027.
Authors
- Zhongcong Xie (ORCID: https://orcid.org/0000-0002-0720-1759)
- Xinchun Mei
- Zihan Ni
- Daniel I. Sessler (ORCID: https://orcid.org/0000-0001-9932-3077)
- Binglei Zhao (ORCID: https://orcid.org/0000-0002-5390-1983)
- Yanyan Wang (ORCID: https://orcid.org/0000-0002-9888-9850)
- Yuan Shen (ORCID: https://orcid.org/0000-0002-7811-1478)
- Jiayi Wang (ORCID: https://orcid.org/0009-0002-9109-0285)
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Mental Health Center (CN)
- Massachusetts General Hospital (US)
- Shanghai Tenth People's Hospital (CN)
- Health Economics and Outcomes Research (United Kingdom) (GB)
- Tongji Hospital (CN)
Publication Details
- Journal
- Trials
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13063-025-09109-w
- Citations
- 2
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.09
Funders
- National Natural Science Foundation of China
- Shanghai Jiao Tong University