In Vivo investigation of xenotransplanted human blood-derived scaffold into mice as a biodegradable construct for improvement of pelvic floor repair
The novel human blood-derived scaffold demonstrated biodegradation and high biocompatibility. Suturing the scaffold on the abdominal wall or back muscle effectively improves clinical symptoms, while further improvements are needed for its clinical application.
Authors
- Fariba Behnia‐Willison (ORCID: https://orcid.org/0000-0001-9742-507X)
- Pouria Aryan (ORCID: https://orcid.org/0000-0003-2844-4706)
- Nadia Willison (ORCID: https://orcid.org/0009-0004-3570-2499)
- Derek Abbott (ORCID: https://orcid.org/0000-0002-0945-2674)
- Tran Nguyen
- Nelson Tansu (ORCID: https://orcid.org/0000-0002-3811-9125)
- Mojdeh Salehnia
Institutions
- Tarbiat Modares University (IR)
- The University of Arizona Global Campus (US)
- The University of Adelaide (AU)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fbioe.2025.1627538
- Citations
- 1
- Primary Topic
- Pelvic floor disorders treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.67