Causal relationship between gut microbiota and pituitary neuroendocrine tumors: a bidirectional Mendelian randomization
Through two-sample Mendelian randomization analysis, we pinpointed particular gut microbiota with a causal link to both the occurrence and prognosis of pituitary neuroendocrine tumors at the genetic prognostic level. These findings hold promise for serving as valuable biomarkers for early disease detection and as potential therapeutic targets for the management of pituitary neuroendocrine tumors.
Authors
- Xianfeng Li (ORCID: https://orcid.org/0000-0001-8549-537X)
- Menghao Liu (ORCID: https://orcid.org/0000-0002-5284-0146)
- Wencai Wang (ORCID: https://orcid.org/0000-0002-0190-5624)
- Zun Wang (ORCID: https://orcid.org/0000-0002-7457-4336)
- Wei Ye (ORCID: https://orcid.org/0009-0003-7331-8650)
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s12672-025-02958-6
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Harbin Medical University
- Second Affiliated Hospital of Harbin Medical University