Primary cardiac endosarcoma: a case report

This case highlights the extreme rarity and poor prognosis of primary cardiac intimal sarcoma and demonstrates that combining surgery, chemotherapy, and targeted therapy may contribute to prolonged survival. These findings suggest the potential role of anlotinib-based therapy for managing MDM2-amplified cardiac intimal sarcoma and warrant further clinical investigation.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-09-26
DOI
https://doi.org/10.1186/s13256-025-05538-y
Citations
2
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
2.78
Controls
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article

Primary cardiac endosarcoma: a case report

Yanhong Luo, Siyu Zhang, S. Zhong, Yunyun Fei
2 citations
Journal of Medical Case Reports
Cardiac tumors and thrombi
2.78
article

Primary cardiac endosarcoma: a case report

Yanhong Luo, Siyu Zhang, S. Zhong, Yunyun Fei
article en
2 citations

Abstract

This case highlights the extreme rarity and poor prognosis of primary cardiac intimal sarcoma and demonstrates that combining surgery, chemotherapy, and targeted therapy may contribute to prolonged survival. These findings suggest the potential role of anlotinib-based therapy for managing MDM2-amplified cardiac intimal sarcoma and warrant further clinical investigation.

Journal of Medical Case ReportsVol. 19(1)
Affiliated Hospital of Hangzhou Normal University (CN)
Openalex Percentile: Top 8%
Cardiac tumors and thrombi
2.78
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