Single-cell RNA sequencing of endometrium uncovers dynamic characteristics and dysregulation of perivascular CD9+SUSD2+ cells in thin endometrium

Our study provides potential molecular mechanisms underpinning perivascular CD9<sup>+</sup> SUSD2<sup>+</sup> cells in the context of thin endometrium. The mechanistic insights could establish new therapeutic strategies for endometrial regeneration and repair.

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Publication Details

Journal
Stem Cell Research & Therapy
Published
2025-09-26
DOI
https://doi.org/10.1186/s13287-025-04658-y
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00

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article

Single-cell RNA sequencing of endometrium uncovers dynamic characteristics and dysregulation of perivascular CD9+SUSD2+ cells in thin endometrium

Lijun Ding, Lianghui Diao, Lingbin Qi, Mai C et al.
Stem Cell Research & Therapy
Reproductive System and Pregnancy
article

Single-cell RNA sequencing of endometrium uncovers dynamic characteristics and dysregulation of perivascular CD9+SUSD2+ cells in thin endometrium

Lijun Ding, Lianghui Diao, Lingbin Qi, Mai C, Mingye Chen, X. Chen, Bo Liang, Tao Zhang
article en

Abstract

Our study provides potential molecular mechanisms underpinning perivascular CD9<sup>+</sup> SUSD2<sup>+</sup> cells in the context of thin endometrium. The mechanistic insights could establish new therapeutic strategies for endometrial regeneration and repair.

Stem Cell Research & TherapyVol. 16(1)
Tongji University (CN), Chinese University of Hong Kong (HK), Nanjing Drum Tower Hospital (CN), Shenzhen Zhongshan Urological Hospital (CN), Tongji Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 72%
Reproductive System and Pregnancy
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