PTX3 as a key modulator of functional ovarian response in PCOS: evaluation alongside TSG-6 and ITI
Elevated follicular PTX-3 levels are linked to hyperandrogenism and ovarian reserve in PCOS, but may impair embryo quality and functional follicular response. PTX-3 may serve as a potential biomarker of ovarian inflammation and compromised oocyte competence, independent of BMI or systemic insulin resistance.
Authors
- Fatma Tanılır Çağıran (ORCID: https://orcid.org/0000-0002-0608-2516)
- Pınar Kirici (ORCID: https://orcid.org/0000-0001-7616-4181)
- Nihal Mavral
- Zercan Kalı (ORCID: https://orcid.org/0000-0002-7128-7550)
- Ümit Karabulut (ORCID: https://orcid.org/0000-0003-3126-2129)
- Tuba Memur
Institutions
- Malatya Turgut Özal Üniversitesi (TR)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Gözde Hastanesi Malatya (TR)
- Ophthalmology Clinic (DE)
- Malatya Devlet Hastanesi (TR)
- Turgut Özal University (TR)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13048-025-01798-w
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00