Analysis of rapid onset heroin overdose cases from a supervised injecting facility in Melbourne, Australia

Rapid onset heroin overdoses typically present as medical emergencies involving severe respiratory depression shortly after heroin administration. Some people appear more likely to experience a rapid onset overdose than others, but factors for this are unclear. Rapid onset heroin overdoses also more commonly occur on some days compared with others, which may indicate an interrelationship between personal risk and the unregulated drug market. Rapid onset overdose cases may play a substantial role in hypoxic-related morbidity and mortality associated with heroin overdoses.

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Publication Details

Journal
Addiction
Published
2025-09-26
DOI
https://doi.org/10.1111/add.70199
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of rapid onset heroin overdose cases from a supervised injecting facility in Melbourne, Australia

Monika Shrestha, John Furler, John Strang, Yvonne Bonomo et al.
Addiction
Opioid Use Disorder Treatment
article

Analysis of rapid onset heroin overdose cases from a supervised injecting facility in Melbourne, Australia

Monika Shrestha, John Furler, John Strang, Yvonne Bonomo, Nathan C. Stam, Basak Tas
article en

Abstract

Rapid onset heroin overdoses typically present as medical emergencies involving severe respiratory depression shortly after heroin administration. Some people appear more likely to experience a rapid onset overdose than others, but factors for this are unclear. Rapid onset heroin overdoses also more commonly occur on some days compared with others, which may indicate an interrelationship between personal risk and the unregulated drug market. Rapid onset overdose cases may play a substantial role in hypoxic-related morbidity and mortality associated with heroin overdoses.

AddictionVol. 121(2)
Royal Women's Hospital (AU), The University of Melbourne (AU), King's College London (GB), St Vincent's Hospital Melbourne (AU), National Health and Medical Research Council (AU), Monash University (AU)
National Institute for Health and Care Research, University of Melbourne, NIHR Maudsley Biomedical Research Centre
Openalex Percentile: Top 65%
Opioid Use Disorder Treatment
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Analysis of rapid onset heroin overdose cases from a supervised injecting facility in Melbourne, Australia — Monika Shrestha, John Furler, et al. · Addiction (2025) | TGRS Research Map | TGRS