Up-regulating methylation of CAP1 promoter can promote apoptosis and inhibit migration and invasion of lung adenocarcinoma cells
Up-regulating CAP1 promoter methylation promotes apoptosis and inhibits migration and invasion of LUAD cells. This suggests that methylating the CAP1 promoter could be a potential therapeutic approach for early-stage LUAD.
Authors
- Guoshu Li (ORCID: https://orcid.org/0000-0002-3083-4837)
- Yunlu Gu
- Jushan Zhang
- Junyong Zou (ORCID: https://orcid.org/0000-0001-5307-2647)
- Kai Wang (ORCID: https://orcid.org/0000-0002-7054-704X)
- Changhui Wang (ORCID: https://orcid.org/0000-0002-7583-6545)
- Yongen Miao (ORCID: https://orcid.org/0009-0004-8723-4965)
- Min Tan (ORCID: https://orcid.org/0000-0003-3996-909X)
- Haoxiang Li (ORCID: https://orcid.org/0000-0002-5072-9065)
- Shuanshuan Xie
Institutions
- Tongji University (CN)
- Ningbo No. 2 Hospital (CN)
- Shanghai Tenth People's Hospital (CN)
- Shanghai Sunshine Rehabilitation Center (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s40001-025-03135-9
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China