Glutamine synthetase shields triple-negative breast cancer cells from ferroptosis in metastasis triggered by glutamine deprivation
This investigation provides insights into the role of ferroptosis in metastasis and demonstrates that GS may be a viable target for preventing metastases in TNBC.
Authors
- Qiao Ye (ORCID: https://orcid.org/0000-0002-0932-0487)
- Guoquan Liu (ORCID: https://orcid.org/0000-0003-0680-4811)
- Guangjin Guo
- Yuan Luo (ORCID: https://orcid.org/0000-0001-8081-7237)
- Xinyu Lian
- Zhaoting Yang
Institutions
- Peking University (CN)
- United States Air Force (US)
- Air Force General Hospital PLA (CN)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13058-025-02115-5
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Natural Science Foundation of China