Bone marrow lesion coexisted with subchondral bone attrition and/or subchondral bone cyst is associated with knee pain in knee osteoarthritis regardless of cartilage lesion: the Bunkyo health study
BML coexistent with SBA and/or SBC, but not BML without the coexistence, was associated with knee pain in the elderly with knee OA regardless of the presence or absence of cartilage lesion.
Authors
- Muneaki Ishijima (ORCID: https://orcid.org/0000-0002-0920-0805)
- S. Wakana
- Kengo Sugitani
- Lizu Liu
- Keiichi Yoshida (ORCID: https://orcid.org/0000-0002-1954-6287)
- Mitsuaki Kubota (ORCID: https://orcid.org/0000-0001-9247-4825)
- S. Hada (ORCID: https://orcid.org/0000-0002-1756-3307)
- Takako Aoki (ORCID: https://orcid.org/0000-0002-9260-4594)
- Jun Shiozawa
- Shuko Nojiri (ORCID: https://orcid.org/0000-0003-0422-8152)
- Yuichiro Machiyama
- Haruka Kaneko (ORCID: https://orcid.org/0000-0003-1239-8653)
- Yuki Someya (ORCID: https://orcid.org/0000-0003-1657-3199)
- Yasunori Okada (ORCID: https://orcid.org/0000-0001-9208-4755)
- Takako Negishi‐Koga (ORCID: https://orcid.org/0000-0002-7780-140X)
- Jun Tomura (ORCID: https://orcid.org/0000-0002-2073-7013)
- Takahiro Sasahara
- Keiji Kobayashi
- Takuya Yamamura
- Yoshifumi Tamura
- Arepati Adili
- Yoshifumi Negishi
Institutions
- Juntendo University (JP)
- Juntendo University Hospital (JP)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13075-025-03644-2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science and Technology
- Academy of Finland
- Vetenskapsrådet
- NordForsk
- Norges Forskningsråd
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency
- Strategic International Collaborative Research Program