The association between dyslipidemia and intervertebral disc degeneration: a prospective cohort study based on the UK biobank
Higher TC and TG levels were associated with increased IDD risk. These findings provide observational evidence for the role of lipid levels in stratifying IDD risk. Routine lipid screening may help identify high-risk individuals and guide early prevention strategies.
Authors
- Wing Fai Choi
- Tongzhou Liang (ORCID: https://orcid.org/0000-0001-5920-5412)
- Wenjie Gao (ORCID: https://orcid.org/0000-0001-9456-8884)
- Huihong Shi (ORCID: https://orcid.org/0009-0002-8910-3307)
- Zhihuai Deng
- Bo Gao (ORCID: https://orcid.org/0000-0001-5213-0286)
- Youxi Lin
- Zaoqiang Zhang
- Wenjun Hu (ORCID: https://orcid.org/0000-0001-8563-8844)
- Song Liu (ORCID: https://orcid.org/0009-0002-6649-4990)
- Jianan Chen (ORCID: https://orcid.org/0000-0002-6673-6884)
- Yanbo Chen (ORCID: https://orcid.org/0000-0003-4210-0598)
- Dongsheng Huang (ORCID: https://orcid.org/0000-0002-9733-7915)
- Peijie Shi
- Nianchun Liao
- Xianjian Qiu
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Sciences (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Peking University Shenzhen Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shenzhen Institutes of Advanced Technology (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12944-025-02687-3
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province