Real-world Prevalence of Nonintegrase INSTI Resistance-Associated Mutations and Virological Outcomes in People Who Have Recently Acquired HIV-1 in the United Kingdom
Several nonintegrase mutations were prevalent, but we found no evidence of an impact upon virological outcomes within treatment-naive individuals on INSTI-based regimens who had recently acquired HIV.
Authors
- Christine Kelly (ORCID: https://orcid.org/0000-0002-3239-7714)
- Daniel Bradshaw (ORCID: https://orcid.org/0000-0001-7186-2482)
- Gary Murphy (ORCID: https://orcid.org/0000-0002-6331-255X)
- Jean L. Mbisa (ORCID: https://orcid.org/0000-0002-0348-9679)
- Anna María Geretti (ORCID: https://orcid.org/0000-0002-3670-6588)
- Hodan Mohamed
- James Lester (ORCID: https://orcid.org/0000-0002-4102-8662)
- David Bibby (ORCID: https://orcid.org/0000-0002-8458-9662)
- Caroline Anne Sabin (ORCID: https://orcid.org/0000-0001-5173-2760)
- Alison Brown (ORCID: https://orcid.org/0000-0002-6490-6739)
Institutions
- University College Dublin (IE)
- University of Rome Tor Vergata (IT)
- University of Liverpool (GB)
- Royal Free London NHS Foundation Trust (GB)
- Public Health England (GB)
- National Institute for Health and Care Research (GB)
- Centre for Research in Engineering Surface Technology (IE)
- Public Health Agency (GB)
- Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool (GB)
- University College London (GB)
- Health and Safety Executive (GB)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1093/infdis/jiaf500
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00