iTr35 cells: a novel immunoregulatory subset involved in bone loss in rheumatoid arthritis and clinical implications
These findings identify iTr35 as a novel immunoregulatory T cell subset potentially involved in protecting against bone loss in RA. This study highlights the significance of iTr35 in osteoimmune regulation and suggests its therapeutic potential in preventing skeletal damage in autoimmune diseases.
Authors
- Lutian Yao (ORCID: https://orcid.org/0000-0002-0652-2075)
- Ming‐Xin An (ORCID: https://orcid.org/0009-0007-2730-4484)
- Yuxuan Li (ORCID: https://orcid.org/0000-0003-1236-578X)
- Jing Lu (ORCID: https://orcid.org/0000-0003-3501-1749)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Liaoning Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1080/07853890.2025.2565438
- Citations
- 2
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 3.34