Inhibition of oxidative stress and the Neuropilin-2-induced neuroinflammatory pathway by EMO ameliorates epileptic seizures in the preclinical model of epilepsy

Emodin alleviates oxidative stress and neuroinflammation by modulating NRP2 and NF-κB pathways, suggesting therapeutic potential in epilepsy.

Authors

Haiting Li (ORCID: https://orcid.org/0000-0002-0883-6406)
Yuehui Li (ORCID: https://orcid.org/0000-0002-4520-1418)
Yangyang Zhang (ORCID: https://orcid.org/0009-0007-8135-2209)
Yujia Zhang (ORCID: https://orcid.org/0000-0001-7991-6385)
Huifang Wang

Institutions

Shanxi Medical University (CN)
First Hospital of Shanxi Medical University (CN)

Publication Details

Journal: Redox Report
Published: 2025-09-25
DOI: https://doi.org/10.1080/13510002.2025.2547405
Citations: 2
Primary Topic: Neuroinflammation and Neurodegeneration Mechanisms
Type: article
Field-Weighted Citation Impact: 1.68

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article

Inhibition of oxidative stress and the Neuropilin-2-induced neuroinflammatory pathway by EMO ameliorates epileptic seizures in the preclinical model of epilepsy

Haiting Li, Yuehui Li, Yangyang Zhang, Yujia Zhang et al.

Sep 25, 2025

2 citations

Redox Report

Neuroinflammation and Neurodegeneration Mechanisms

1.68

article

Inhibition of oxidative stress and the Neuropilin-2-induced neuroinflammatory pathway by EMO ameliorates epileptic seizures in the preclinical model of epilepsy

Haiting Li, Yuehui Li, Yangyang Zhang, Yujia Zhang, Huifang Wang

September 25, 2025article en

2 citations

Abstract

Emodin alleviates oxidative stress and neuroinflammation by modulating NRP2 and NF-κB pathways, suggesting therapeutic potential in epilepsy.

Redox ReportVol. 30(1)

Shanxi Medical University (CN), First Hospital of Shanxi Medical University (CN)

Openalex Percentile: Top 13%

Neuroinflammation and Neurodegeneration Mechanisms

1.68

DOI Open Access PDF OpenAlex

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Inhibition of oxidative stress and the Neuropilin-2-induced neuroinflammatory pathway by EMO ameliorates epileptic seizures in the preclinical model of epilepsy — Haiting Li, Yuehui Li, et al. · Redox Report (2025) | TGRS Research Map | TGRS