SPP1 as a biomarker for idiopathic membranous nephropathy progression and its regulatory role in inflammation and fibrosis
SPP1 was identified as a promising biomarker for IMN, demonstrating a critical role in promoting fibrosis and inflammatory responses associated with the disease. These findings suggest its potential as a novel therapeutic target for IMN intervention.
Authors
- Chao Xue (ORCID: https://orcid.org/0000-0001-5671-1969)
- Bingmei Feng (ORCID: https://orcid.org/0009-0000-4566-2532)
- Xuesong Chen (ORCID: https://orcid.org/0009-0001-1185-8470)
- Zige Liu (ORCID: https://orcid.org/0000-0002-6659-3692)
- Shuting Pang (ORCID: https://orcid.org/0009-0001-2481-4581)
- Rongbin Zhou (ORCID: https://orcid.org/0000-0002-3351-6420)
- Boyu Zhao (ORCID: https://orcid.org/0000-0002-2521-2443)
- Qi Tan (ORCID: https://orcid.org/0000-0002-3384-3544)
- Weidong Li (ORCID: https://orcid.org/0000-0003-0521-7412)
- Shanshan Li (ORCID: https://orcid.org/0000-0001-6443-958X)
- Yuli Xie
- Fugang Liu (ORCID: https://orcid.org/0009-0003-0790-6219)
- Hong Chen (ORCID: https://orcid.org/0009-0004-5991-0372)
- Boji Xie
- Liangping Ruan
- Rirong Yang (ORCID: https://orcid.org/0009-0005-5349-343X)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Center for Genomic Science (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1671891
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 2.86