Biological Advantages of Calcium Hypochlorite Solution Over Sodium Hypochlorite for Regenerative Endodontic Procedures: An Ex Vivo and In Vitro Study on Human Apical Papilla
Ca(OCl)<sub>2</sub> at 1.5% caused less structural damage to AP than NaOCl at the same concentration and had a more favourable influence on the viability, proliferation and osteogenic differentiation of hAPCs. Moreover, it did not impair cell chemotaxis. These findings suggest that Ca(OCl)<sub>2</sub> may offer biological advantages in regenerative endodontic procedures.
Authors
- Paulo Sérgio Cerri (ORCID: https://orcid.org/0000-0001-5756-5828)
- Gisele Faria (ORCID: https://orcid.org/0000-0001-7030-3718)
- Luana Raphael da Silva (ORCID: https://orcid.org/0000-0001-5560-3587)
- Hernán Coaguila‐Llerena (ORCID: https://orcid.org/0000-0002-9991-718X)
- Barbara ROMA (ORCID: https://orcid.org/0000-0002-7694-4732)
- Eduardo de Medeiros Ferraz (ORCID: https://orcid.org/0009-0007-0906-8414)
- Carlos Rossa (ORCID: https://orcid.org/0000-0003-1705-5481)
Institutions
- Morpho (United States) (US)
- Universidad Peruana Cayetano Heredia (PE)
- Centro Universitário de Araraquara (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1111/iej.70038
- Citations
- 1
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.79