FAHD1 prevents neuronal ferroptosis by modulating R-loop and the cGAS–STING pathway
FAHD1 is a critical regulator of neuronal ferroptosis and may serve as a potential therapeutic target for the treatment of neurodegenerative diseases and CNS injuries.
Authors
- Yuxuan Zhou (ORCID: https://orcid.org/0000-0002-7919-8341)
- Zixian Zeng (ORCID: https://orcid.org/0000-0001-8572-9121)
- Yubiao Yang
- Xianhu Zhou (ORCID: https://orcid.org/0009-0002-5420-0190)
- Jinyu Chen (ORCID: https://orcid.org/0000-0002-7039-9091)
- Jian Hao (ORCID: https://orcid.org/0000-0001-9705-3771)
- Cheng Tang
- Boyuan Ma (ORCID: https://orcid.org/0000-0002-7486-9556)
- Bitao Wang
- Zhenhan Li (ORCID: https://orcid.org/0000-0002-1989-0539)
Institutions
- Ningbo University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Ningbo College of Health Sciences (CN)
- Cadence Design Systems (United States) (US)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Open Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/med-2025-1200
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00