Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy
This study reveals immune-related mechanistic biomarkers and potential therapeutic targets in HCM, highlighting the role of immune dysregulation in disease progression. Machine learning and SHAP analysis improved diagnostic model interpretability, providing a basis for future development of non-invasive diagnostic tools.
Authors
- Qingxiao Nong
- Dalang Fang (ORCID: https://orcid.org/0000-0001-9064-6283)
- Jinfeng Wang (ORCID: https://orcid.org/0000-0002-6687-9420)
- Q. Liang
- Shouwen Tao
Institutions
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Baise University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1645382
- Citations
- 2
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 1.59