The Role of Urinary Secretory Immunoglobulin A in the Pathophysiology of Interstitial Cystitis

Although no significant differences in urinary sIgA levels were observed between BPS/IC patients and healthy controls, subgroup analyses identified associations with smoking and cardiac comorbidities. These findings suggest that sIgA may be relevant to BPS/IC pathophysiology and highlight the potential of mucosal immune biomarkers. Larger studies are warranted to further clarify the role of sIgA in BPS/IC.

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Publication Details

Journal
International Neurourology Journal
Published
2025-09-26
DOI
https://doi.org/10.5213/inj.2550048.024
Primary Topic
Urinary Bladder and Prostate Research
Type
article
Field-Weighted Citation Impact
0.00

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article

The Role of Urinary Secretory Immunoglobulin A in the Pathophysiology of Interstitial Cystitis

Fuat Kızılay, Adnan Şimşir, Kasım Emre Ergün, Bayram Aliyev et al.
International Neurourology Journal
Urinary Bladder and Prostate Research
article

The Role of Urinary Secretory Immunoglobulin A in the Pathophysiology of Interstitial Cystitis

Fuat Kızılay, Adnan Şimşir, Kasım Emre Ergün, Bayram Aliyev, Serdar Kalemci, Elif Azarsız, Turan Özdemir
article en

Abstract

Although no significant differences in urinary sIgA levels were observed between BPS/IC patients and healthy controls, subgroup analyses identified associations with smoking and cardiac comorbidities. These findings suggest that sIgA may be relevant to BPS/IC pathophysiology and highlight the potential of mucosal immune biomarkers. Larger studies are warranted to further clarify the role of sIgA in BPS/IC.

International Neurourology JournalVol. 29(3)
Ege University (TR)
Ege Üniversitesi
Openalex Percentile: Top 63%
Urinary Bladder and Prostate Research
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