Blood culture positive sepsis in England, 2017–2018: epidemiological assessment of the commissioning for quality and innovation (CQUIN) sepsis indicator
This study provides novel insights into the epidemiology of sepsis screening in emergency departments across England, highlighting variability in blood culture positivity rates and microbial profiles. The findings underscore the importance of enhanced surveillance strategies, optimised screening protocols, tailored antimicrobial stewardship practices, and quality improvement initiatives to optimise sepsis management and outcomes. Systemic approaches are needed to address knowledge gaps and inform evidence-based interventions for sepsis care.
Authors
- Ranya Mulchandani (ORCID: https://orcid.org/0000-0002-5157-1060)
- André Charlett (ORCID: https://orcid.org/0000-0001-7154-0432)
- Alex Bhattacharya (ORCID: https://orcid.org/0000-0003-3000-2771)
- Susan Hopkins (ORCID: https://orcid.org/0000-0001-5179-5702)
- Rosy Reynolds (ORCID: https://orcid.org/0000-0003-4643-9556)
- Russell Hope (ORCID: https://orcid.org/0000-0003-2838-6833)
- Simon Packer (ORCID: https://orcid.org/0000-0002-9157-3650)
- Isabel Oliver (ORCID: https://orcid.org/0000-0002-6106-1734)
- Joshua Howkins (ORCID: https://orcid.org/0000-0002-4289-2946)
- Colin Stewart Brown (ORCID: https://orcid.org/0000-0003-4776-3403)
- Theresa Lamagni (ORCID: https://orcid.org/0000-0002-3965-8323)
- Carla Robinson
Institutions
- Environment Agency (GB)
- National Institute for Health and Care Research (GB)
- University of Bristol (GB)
- UK Health Security Agency (GB)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12879-025-11539-5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health Research Health Protection Research Unit
- National Institute for Health and Care Research
- University of Bristol