Evaluating the diagnostic efficacy of metagenomic next-generation sequencing in bronchoalveolar lavage fluid for pulmonary cryptococcosis with different clinical and imaging characteristics
BALF-mNGS demonstrated high sensitivity for diagnosing PC, particularly in patients presenting with cough or sputum, right lung lesions, or multiple lesions. This serves as a valuable tool for the early diagnosis of PC.
Authors
- Shanhong Lin (ORCID: https://orcid.org/0000-0001-7632-6478)
- Mei Chen (ORCID: https://orcid.org/0000-0001-6809-147X)
- Limin Chen (ORCID: https://orcid.org/0000-0002-1082-9838)
- Chao Cao (ORCID: https://orcid.org/0000-0002-0455-1171)
- Ning Zhu
- Yan Zhang (ORCID: https://orcid.org/0000-0002-4835-8541)
Institutions
- Ningbo University (CN)
- Fujian Medical University (CN)
- Union Hospital (US)
- Ningbo University Affiliated Hospital (CN)
- Union Hospital (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12879-025-11574-2
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province