Etiology and antimicrobial resistance patterns of sepsis in infants 0–59 days old in Jimma, Ethiopia: a longitudinal study
Isolates from PSBI showed high rates of antibiotic resistance to first- and second-line antimicrobials. In this setting, the WHO empiric treatment guidelines inadequately treat infants admitted with PSBI, particularly those with Klebsiella. To provide the most effective care for PSBI in 0-59 days old infants, institutionally used guidelines should be customized to reflect local epidemiology and resistance patterns.
Authors
- James H. Conway (ORCID: https://orcid.org/0000-0001-6040-403X)
- Alemseged Abdissa (ORCID: https://orcid.org/0000-0003-3798-5037)
- Daniele Y Gusland
- Jens C. Eickhoff (ORCID: https://orcid.org/0000-0003-0525-6462)
- Mulatu Gashaw
- Dawd S. Siraj (ORCID: https://orcid.org/0000-0002-4433-9773)
- Melkamu Berhane
- Mekdes Shimekit
Institutions
- University of Wisconsin–Madison (US)
- Jimma University (ET)
- University of California, San Francisco (US)
- Ghent University (BE)
- St. Paul's Hospital Millennium Medical College (ET)
- Armauer Hansen Research Institute (ET)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13756-025-01626-2
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00