Cytological and Molecular Genetic Screening of the Impact of Radiation Contamination on the Human Genome and Public Health (Cytogenetic, Genome Variation)
Environmental radiation exposure remains a significant public health concern in Kazakhstan, particularly in regions surrounding legacy uranium mining sites and radioactive waste repositories.This study presents a comprehensive assessment of genomic instability and related health outcomes among affected populations.A multidisciplinary approach was employed, combining radiological monitoring, cytogenetic assays, and molecular genetic profiling.Electron paramagnetic resonance (EPR) dosimetry of dental enamel indicated elevated cumulative radiation doses exceeding 25-30 rad in exposed individuals.Cytogenetic analyses revealed significantly increased frequencies of
Authors
- Oksana Cherednichenko (ORCID: https://orcid.org/0000-0001-5681-639X)
- Leila Adilova (ORCID: https://orcid.org/0000-0001-8048-6116)
- Bakhytzhan Bekmanov (ORCID: https://orcid.org/0000-0002-2232-0481)
- Aizada Kozhakhmetova (ORCID: https://orcid.org/0000-0002-5311-8083)
- Ayaulym Myrzatay (ORCID: https://orcid.org/0000-0002-4830-2310)
- Klara Shalabaeva
- Aitkhazha Bigaliev
- Amangeldy Kulimbetov
- Raikhan Zhumanova
- Kenzheyeva Kenzheyeva
- Ruslan Salmurzauly
Publication Details
- Journal
- ES Energy & Environments
- Published
- 2025-01-01
- DOI
- https://doi.org/10.30919/ee1744
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00