Divergent selection for litter size variability affects RNA cargo in oviductal extracellular vesicles related to embryonic development and survival
This is the first study unveiling the differential oEV RNA cargo between lines selected for low versus high variation in litter size, and in each line, between P and NO does. The changes in protein-coding RNA and miRNA cargo might reflect the different maternal support to the early embryo development in the different lines.
Authors
- C. Almiñana (ORCID: https://orcid.org/0000-0003-0495-7099)
- M. L. García (ORCID: https://orcid.org/0000-0001-9504-8290)
- M. J. Argente (ORCID: https://orcid.org/0000-0002-4541-3293)
- Daniel Serrano-Jara
- Stefan Bauersachs (ORCID: https://orcid.org/0000-0003-2450-1216)
- Meriem Hamdi (ORCID: https://orcid.org/0000-0002-5210-4915)
Institutions
- Universitat de Miguel Hernández d'Elx (ES)
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Centro de Investigación y Tecnología Agroalimentaria de Aragón (ES)
Publication Details
- Journal
- Biological Research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s40659-025-00642-1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Functional Genomics Center Zurich