Pilot study of association between neonatal brain perivascular space volume and neurodevelopmental outcomes at 24 months

In this pilot study, larger BG-PVS volume in neonates at term-equivalent age was associated with poorer developmental outcomes at 24 months. These preliminary findings suggest that BG-PVS volume may warrant further investigation as a potential early imaging biomarker for neurodevelopmental risk assessment in neonates, though larger studies are needed to confirm these associations.

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Publication Details

Journal
BMC Medical Imaging
Published
2025-09-26
DOI
https://doi.org/10.1186/s12880-025-01912-w
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
0.00

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article

Pilot study of association between neonatal brain perivascular space volume and neurodevelopmental outcomes at 24 months

Hyun Gi Kim, Yoonho Nam, Ah‐Ra Cho, Arum Choi et al.
BMC Medical Imaging
Neonatal and fetal brain pathology
article

Pilot study of association between neonatal brain perivascular space volume and neurodevelopmental outcomes at 24 months

Hyun Gi Kim, Yoonho Nam, Ah‐Ra Cho, Arum Choi, Daniel Bąk, Hosna Asma-ull
article en

Abstract

In this pilot study, larger BG-PVS volume in neonates at term-equivalent age was associated with poorer developmental outcomes at 24 months. These preliminary findings suggest that BG-PVS volume may warrant further investigation as a potential early imaging biomarker for neurodevelopmental risk assessment in neonates, though larger studies are needed to confirm these associations.

BMC Medical ImagingVol. 25(1)
Ulsan College (KR), Asan Medical Center (KR), University of Ulsan (KR), St. Mary's Hospital (US), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Hankuk University of Foreign Studies (KR), Catholic University of Korea (KR)
National Research Foundation, National Research Foundation of Korea
Openalex Percentile: Top 63%
Neonatal and fetal brain pathology
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