A novel self-inhaled nicotine exposure system in murine models reveals age-dependent metabolic effects of nicotine
Our novel e-liquid-based inhalation model provides a valuable tool for studying nicotine's physiological and behavioral effects, with implications for understanding smoking-related health risks and addiction mechanisms.
Authors
- Longlong Tu (ORCID: https://orcid.org/0000-0002-6955-6002)
- Yongxiang Li (ORCID: https://orcid.org/0000-0002-0631-5391)
- Olivia Z. Ginnard (ORCID: https://orcid.org/0000-0002-8175-6357)
- Yongjie Yang (ORCID: https://orcid.org/0000-0003-0318-8224)
- Qingzhuo Liu (ORCID: https://orcid.org/0009-0003-1243-2783)
- Yong Xu (ORCID: https://orcid.org/0000-0002-4908-1572)
- Tong Zhou (ORCID: https://orcid.org/0000-0003-3844-1576)
- Fuhui Wang
- Yutian Liu (ORCID: https://orcid.org/0000-0001-6932-5207)
- Kristie Conde (ORCID: https://orcid.org/0000-0002-9525-4606)
- Ya-Hui Shi (ORCID: https://orcid.org/0009-0006-2460-0889)
- Yue Deng (ORCID: https://orcid.org/0000-0001-8874-911X)
- Meixin Sun
- Jinjing Jian
- Xing Fang (ORCID: https://orcid.org/0000-0001-9349-799X)
- Hailan Liu (ORCID: https://orcid.org/0000-0001-5737-9240)
- Sanika V Jossy (ORCID: https://orcid.org/0009-0007-9619-7985)
- Xu Xu (ORCID: https://orcid.org/0000-0001-8790-3103)
- Mengjie Wang (ORCID: https://orcid.org/0000-0002-7553-4977)
- Xi Wu (ORCID: https://orcid.org/0000-0002-0667-8117)
- Chunmei Wang (ORCID: https://orcid.org/0000-0001-9615-0828)
- Jingjing Cheng (ORCID: https://orcid.org/0000-0002-9348-2322)
- Junying Han
- Meng Yu (ORCID: https://orcid.org/0000-0002-8007-3378)
- Yuxue Yang
- Xinming Liu
- Jiamin Qiu
- Megan E Burt
- Darah Ave Threat
Institutions
- Baylor College of Medicine (US)
- Children's Nutrition Research Center at Baylor College of Medicine (US)
- Texas Children's Hospital (US)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13578-025-01473-z
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 0.00