Ginseng Polysaccharides Inhibit Aspergillus sydowii-Driven Lung Adenocarcinoma via Modulating Gut Microbiota–Bile Acid Metabolism Axis
GPs exert antitumor effects against <i>A. sydowii</i>-induced LUAD by modulating gut microbiota and bile acid metabolism. This identifies GPs as a promising therapy for mycobiome-influenced cancers, with dual targeting of fungal infection and metabolic reprogramming.
Authors
- Li-Rong Lian
- Guangxu Ma (ORCID: https://orcid.org/0000-0002-5929-7887)
- Feng Zhou (ORCID: https://orcid.org/0000-0002-2402-4774)
- Young-Ho Song (ORCID: https://orcid.org/0000-0002-3430-1544)
- Hudan Pan
- Yicheng Zhao
- Jinlian He (ORCID: https://orcid.org/0000-0002-9961-2482)
- Liang Liu (ORCID: https://orcid.org/0000-0002-1186-6497)
- Mingming Wang (ORCID: https://orcid.org/0009-0005-9972-5056)
- Xiao Shu (ORCID: https://orcid.org/0000-0002-6553-3911)
- Liqing Chen (ORCID: https://orcid.org/0000-0002-4857-2097)
- Runze Li
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shandong Academy of Chinese Medicine (CN)
Publication Details
- Journal
- Cancers
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3390/cancers17193134
- Citations
- 2
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.61