Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation

<b>Background/Objectives</b>: Understanding the diverse neuron types within the hippocampal formation is essential for advancing our knowledge of its fundamental roles in learning and memory. Hippocampome.org serves as a comprehensive, evidence-based knowledge repository that integrates morphological, electrophysiological, and molecular features of neurons across the rodent dentate gyrus, CA3, CA2, CA1, subiculum, and entorhinal cortex. In addition to these core properties, this open access resource includes detailed information on synaptic connectivity, signal propagation, and plasticity, facilitating sophisticated modeling of hippocampal circuits. A distinguishing feature of Hippocampome.org is its emphasis on quantitative, literature-backed data that can help constrain and validate spiking neural network simulations via an interactive web interface. <b>Methods</b>: To assess and enhance its utility to the neuroscience community, we integrated Google Analytics (GA) into the platform to monitor user behavior, identify high-impact content, and evaluate geographic reach. <b>Results</b>: GA data provided valuable page view metrics, revealing usage trends, frequently accessed neuron properties, and the progressive adoption of new functionalities. <b>Conclusions</b>: These insights directly inform iterative development, particularly in the design of a robust Application Programming Interface (API) to support programmatic access. Ultimately, the integration of GA empowers data-driven optimization of this public resource to better serve the global neuroscience community.

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Publication Details

Journal
Biomedicines
Published
2025-09-26
DOI
https://doi.org/10.3390/biomedicines13102363
Citations
1
Primary Topic
Cognitive Science and Mapping
Type
article
Field-Weighted Citation Impact
2.48
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article

Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation

Diek W. Wheeler, Giorgio A. Ascoli, Kasturi Nadella
1 citations
Biomedicines
Cognitive Science and Mapping
2.48
article

Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation

Diek W. Wheeler, Giorgio A. Ascoli, Kasturi Nadella
article en
1 citations

Abstract

<b>Background/Objectives</b>: Understanding the diverse neuron types within the hippocampal formation is essential for advancing our knowledge of its fundamental roles in learning and memory. Hippocampome.org serves as a comprehensive, evidence-based knowledge repository that integrates morphological, electrophysiological, and molecular features of neurons across the rodent dentate gyrus, CA3, CA2, CA1, subiculum, and entorhinal cortex. In addition to these core properties, this open access resource includes detailed information on synaptic connectivity, signal propagation, and plasticity, facilitating sophisticated modeling of hippocampal circuits. A distinguishing feature of Hippocampome.org is its emphasis on quantitative, literature-backed data that can help constrain and validate spiking neural network simulations via an interactive web interface. <b>Methods</b>: To assess and enhance its utility to the neuroscience community, we integrated Google Analytics (GA) into the platform to monitor user behavior, identify high-impact content, and evaluate geographic reach. <b>Results</b>: GA data provided valuable page view metrics, revealing usage trends, frequently accessed neuron properties, and the progressive adoption of new functionalities. <b>Conclusions</b>: These insights directly inform iterative development, particularly in the design of a robust Application Programming Interface (API) to support programmatic access. Ultimately, the integration of GA empowers data-driven optimization of this public resource to better serve the global neuroscience community.

BiomedicinesVol. 13(10)
George Mason University (US)
Openalex Percentile: Top 8%
Cognitive Science and Mapping
2.48
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