Insight into the Roles of Albumin—Alone and in Combination with Either Voriconazole or Antimicrobial Peptides Derived from Chromogranin A—In the Growth of Different Microbial Species

Our experiments support the fact that albumins display intrinsic antimicrobial properties, with an unpredictable growth inhibitory effect on various microbes. ThHSA can thus be an adjunctive tool for more efficient care of some, though not all, infections. The interaction of BSA with catestatin and cateslytin is related to their structure, with BSA significantly enhancing the effect of catestatin but not that of cateslytin.

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Publication Details

Journal
Antibiotics
Published
2025-09-26
DOI
https://doi.org/10.3390/antibiotics14100974
Primary Topic
Microbial Metabolites in Food Biotechnology
Type
article
Field-Weighted Citation Impact
0.00

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article

Insight into the Roles of Albumin—Alone and in Combination with Either Voriconazole or Antimicrobial Peptides Derived from Chromogranin A—In the Growth of Different Microbial Species

Francesco Scavello, Pierre Schaaf, Sophie Hellé, Jean‐Marc Strub et al.
Antibiotics
Microbial Metabolites in Food Biotechnology
article

Insight into the Roles of Albumin—Alone and in Combination with Either Voriconazole or Antimicrobial Peptides Derived from Chromogranin A—In the Growth of Different Microbial Species

Francesco Scavello, Pierre Schaaf, Sophie Hellé, Jean‐Marc Strub, Francis Schneider, Philippe Lavall�e, Marie‐Hélène Metz‐Boutigue, François-Xavier von Hunolstein
article en

Abstract

Our experiments support the fact that albumins display intrinsic antimicrobial properties, with an unpredictable growth inhibitory effect on various microbes. ThHSA can thus be an adjunctive tool for more efficient care of some, though not all, infections. The interaction of BSA with catestatin and cateslytin is related to their structure, with BSA significantly enhancing the effect of catestatin but not that of cateslytin.

AntibioticsVol. 14(10)
Centre National de la Recherche Scientifique (FR), Inserm (FR), IRCCS Humanitas Research Hospital (IT), Université de Strasbourg (FR)
Institut National de la Santé et de la Recherche Médicale, Université de Strasbourg, Università della Calabria
Openalex Percentile: Top 68%
Microbial Metabolites in Food Biotechnology
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