Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review
Both antiretroviral therapy and HIV influence the gut microbiota in infants born to MWH. Pathogenic overgrowth within the infant gut microbiota for individuals with HIV may impair immune maturation during early-life, with lasting consequences for host health.Contribution: This highlights the need for further research into probiotic interventions for infants in high HIV-burden settings.
Authors
- Runyararo Mashingaidze-Mano (ORCID: https://orcid.org/0000-0002-2089-182X)
- Danai Tavonga Zhou (ORCID: https://orcid.org/0000-0001-7907-2442)
- Taona Emmah Mudhluli (ORCID: https://orcid.org/0000-0002-9743-2023)
- Lindsay J. Hall (ORCID: https://orcid.org/0000-0001-8938-5709)
- Inam Chitsike (ORCID: https://orcid.org/0000-0002-9837-8372)
- Justen Manasa (ORCID: https://orcid.org/0000-0002-8874-907X)
- Exnevia Gomo (ORCID: https://orcid.org/0000-0003-0891-6251)
Institutions
- University of Zimbabwe (ZW)
- University of Namibia (NA)
- Midlands State University (ZW)
- University of Birmingham (GB)
Publication Details
- Journal
- African Journal of Primary Health Care & Family Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.4102/phcfm.v17i1.4939
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00