Sequential immunotherapy with tofacitinib and low-dose IL-2 induces sustained remission in alopecia areata: a proof-of-concept monocentric study

Sequential tofacitinib and low-dose IL-2 therapy may reestablish immune tolerance, offering a potential strategy for drug-free remission. Larger trials are needed to confirm efficacy and optimize protocols.

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Publication Details

Journal
QJM
Published
2025-09-24
DOI
https://doi.org/10.1093/qjmed/hcaf221
Citations
1
Primary Topic
Hair Growth and Disorders
Type
article
Field-Weighted Citation Impact
1.84
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article

Sequential immunotherapy with tofacitinib and low-dose IL-2 induces sustained remission in alopecia areata: a proof-of-concept monocentric study

Wei Feng Shi, Jundong Huang, Jui-Jiun Jian, Ji Li et al.
1 citations
QJM
Hair Growth and Disorders
1.84
article

Sequential immunotherapy with tofacitinib and low-dose IL-2 induces sustained remission in alopecia areata: a proof-of-concept monocentric study

Wei Feng Shi, Jundong Huang, Jui-Jiun Jian, Ji Li, Min Li, Yan Tang, Zhixiang Zhao, Fangfen Liu, Ruxin Ji, X. H. Liang
article en
1 citations

Abstract

Sequential tofacitinib and low-dose IL-2 therapy may reestablish immune tolerance, offering a potential strategy for drug-free remission. Larger trials are needed to confirm efficacy and optimize protocols.

QJMVol. 119(2)
Central South University (CN), Xiangya Hospital Central South University (CN)
Openalex Percentile: Top 13%
Hair Growth and Disorders
1.84
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