A multifaceted hybrid ES-robotic device for gait training in individuals with neurological disorders

The integration of robotics and Electrical Stimulation (ES) in neurorehabilitation leverages robotics' precise task execution alongside ES-induced motor learning, muscle conditioning, and cardiovascular benefits. We propose a hybrid system for overground gait training, combining neuromuscular ES and a motorized exoskeleton. Different combination modalities are proposed: ES-motor cooperation for the swinging knee, synchronized but independent ES and motor assistance for hip movements and for the knee during stance, and ES-only for the non-actuated ankle. Twelve non-disabled subjects and eleven participants with neurological disorders tested the system under two conditions: exoskeleton-only and hybrid. The hybrid condition reduced knee motor torque by 48% during swing without compromising tracking accuracy, showing that ES can effectively drive limb motion. Neurological participants rated the hybrid system as more usable than the exoskeleton alone (median 5-point improvement of System Usability Scale). These findings support the feasibility of hybrid ES-motorized exoskeletons in clinical settings. Future studies should investigate their potential to enhance therapeutic outcomes.

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Publication Details

Journal
Nature Communications
Published
2025-09-26
DOI
https://doi.org/10.1038/s41467-025-63474-3
Citations
2
Primary Topic
Stroke Rehabilitation and Recovery
Type
article
Field-Weighted Citation Impact
2.05

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article

A multifaceted hybrid ES-robotic device for gait training in individuals with neurological disorders

Stefano Maludrottu, Alessandra Pedrocchi, Francesca Dell’Eva, Giancarlo Ferrigno et al.
2 citations
Nature Communications
Stroke Rehabilitation and Recovery
2.05
article

A multifaceted hybrid ES-robotic device for gait training in individuals with neurological disorders

Stefano Maludrottu, Alessandra Pedrocchi, Francesca Dell’Eva, Giancarlo Ferrigno, Marta Gandolla, Emanuele Gruppioni, Eleonora Guanziroli, Emilia Ambrosini, Franco Molteni, Laura Brignole, Viola Camerini
article en
2 citations

Abstract

The integration of robotics and Electrical Stimulation (ES) in neurorehabilitation leverages robotics' precise task execution alongside ES-induced motor learning, muscle conditioning, and cardiovascular benefits. We propose a hybrid system for overground gait training, combining neuromuscular ES and a motorized exoskeleton. Different combination modalities are proposed: ES-motor cooperation for the swinging knee, synchronized but independent ES and motor assistance for hip movements and for the knee during stance, and ES-only for the non-actuated ankle. Twelve non-disabled subjects and eleven participants with neurological disorders tested the system under two conditions: exoskeleton-only and hybrid. The hybrid condition reduced knee motor torque by 48% during swing without compromising tracking accuracy, showing that ES can effectively drive limb motion. Neurological participants rated the hybrid system as more usable than the exoskeleton alone (median 5-point improvement of System Usability Scale). These findings support the feasibility of hybrid ES-motorized exoskeletons in clinical settings. Future studies should investigate their potential to enhance therapeutic outcomes.

Nature CommunicationsVol. 16(1)
Italian Institute of Technology (IT), Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro (IT), Ospedale Valduce (IT), Politecnico di Milano (IT)
Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro
Openalex Percentile: Top 11%
Stroke Rehabilitation and Recovery
2.05
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