Association of Antipsychotic Dose with Surrogate Efficacy and Safety Outcomes in Hospitalized Older Adults: A Retrospective Cohort Study
Low- and high-dose antipsychotics demonstrated similar short-term efficacy, but higher doses may carry increased risk of adverse events in hospitalized older adults. Clinicians should prioritize low-dose regimens and evaluate the necessity of antipsychotic use in this vulnerable population.
Authors
- Nicole E. Cieri‐Hutcherson (ORCID: https://orcid.org/0000-0002-2861-3074)
- Stephanie Seyse (ORCID: https://orcid.org/0009-0009-1982-3975)
- Collin M. Clark (ORCID: https://orcid.org/0000-0003-3509-9779)
- Ashley E. Woodruff (ORCID: https://orcid.org/0000-0003-2378-1842)
- Nicole M. Sarisky
Institutions
- Buffalo General Medical Center (US)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Drugs & Aging
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s40266-025-01250-0
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00